PATIENT INFORM ATION
LATISSE®
(la teece)
(bimatoprost ophthalmic solution)
0
.
03
%
Read the Patient Information that comes with L A T IS S E ® before
you start using it and each time you get a refill. There may be new
information.This leaflet does not take the place of talking with your
physician about your treatment.
W hat is hypotrichosis of the eyelashes?
Hypotrichosis is another name for having inadequate or not enough
eyelashes.
W hat is LATISSE® solution?
LATISSE®
solution is a prescription treatment for hypotrichosis used
to grow eyelashes, making them longer,
thicker and darker.
Who should N O T take LATISSE®?
Do not use
LATISSE®
solution if you are allergic to one of its
ingredients.
Are there any special warnings associated with LATISSE®
use?
LATISSE®
solution is intended for
use on the skin of the
upper eyelid margins at the base of the eyelashes.
Refer
to Illustration
2
.
DO N O T APPLY
to the lower eyelid. If you are
using
LUMIGAN®
or other products in the same class for elevated
intraocular pressure (IOP). or if you have a history of abnormal IOR
you should only use
LATISSE®
under the close supervision of your
physician.
LATISSE®
use may cause darkening of the eyelid skin which may
be reversible.
LATISSE®
use may also cause increased brown
pigmentation of the colored part of the eye which is likely to be
permanent.
It is possible for hair growth to occur in other areas of your skin that
LATISSE
'
frequently touches. Any excess solution outside the upper
eyelid margin should be blotted with a tissue or other absorbent
material to reduce the chance of this from happening. It is also possible
for a difference in eyelash length, thickness, fullness, pigmentation,
number of eyelash hairs, and/or direction of eyelash growth to occur
between eyes.These differences, should they occur, will usually go away
if you stop using
LATISSE®
Who should I tell that I am using LATISSE®?
You should tell your physician you are using
LATISSE®
especially if
you have a history of eye pressure problems.
You should also tell anyone conducting an eye pressure screening that
you are using
LATISSE®
W hat should I do if I get LATISSE® in my eye?
LATISSE
' solution is an ophthalmic drug product.
LATISSE®
is not
expected to cause harm if it gets into the eye proper.
Do not attempt
to rinse your eye in this situation.
W hat are the possible side effects of LATISSE®?
The most common side effects after using
LATISSE®
solution are an
itching sensation in the eyes and/or eye redness.This was reported in
approximately
4
% of patients.
LATISSE®
solution may cause other
less common side effects which typically occur on the skin close
to where
LATISSE®
is applied, or in the eyes.These include skin
darkening, eye irritation, dryness of the eyes, and redness of the eyelids.
If you develop a new ocular condition (e.g.
. trauma or infection),
experience a sudden decrease in visual acuity, have ocular surgery,
or develop any ocular reactions, particularly conjunctivitis and eyelid
reactions, you should immediately seek your physician's advice
concerning the continued use of
LATISSE®
solution.
W hat happens if I stop using LATISSE®?
If you stop using
LATISSE®
your eyelashes are expected to return to
their previous appearance over several weeks to months.
Any eyelid skin darkening is expected to reverse after several weeks to
months.
Any darkening of the colored part of the eye known as the iris is N O T
expected to reverse and is likely permanent.
How do I use LATISSE®?
LATISSE®
solution is packaged as a
3
mL bottle of solution with
60
accompanying sterile, disposable applicators.The recommended dosage
is one application nightly to the skin of the upper eyelid margin at the
base of the eyelashes only.
Once nightly, start by ensuring your face is clean, makeup and contact
lenses are removed. Remove an applicator from its tray. Then, holding
the sterile applicator horizontally, place one drop of
LATISSE®
on
the area of the applicator closest to the tip but not on the tip (see
Illustration
I ).Then immediately draw the applicator carefully across
the skin of the upper eyelid margin at the base of the eyelashes (where
the eyelashes meet the skin) going from the inner part of your lash line
to the outer part (see Illustration
2
). Blot any excess solution beyond
the eyelid margin. Dispose of the applicator after one use.
Repeat for the opposite upper eyelid margin using a new sterile
applicator.This helps minimize any potential for contamination from
one eyelid to another.
ILLUSTRATION I
ILLUSTRATION
2
DO N O T APPLY
in your eye or to the lower lid.
O NLY
use the
sterile applicators supplied with
LATISSE®
to apply the product. If
you miss a dose, don't try to "catch up." Just apply
LATISSE®
solution
the next evening. Fifty percent of patients treated with
LATISSE®
in a clinical study saw significant improvement by 2 months after
starting treatment.
If any
LATISSE®
solution gets into the eye proper, it is not expected
to cause harm.The eye should not be rinsed.
Don't allow the tip of the bottle or applicator to contact surrounding
structures, fingers, or any other unintended surface in order to avoid
contamination by common bacteria known to cause infections.
Contact lenses should be removed prior to application of
LATISSE®
and may be reinserted
15
minutes following its administration.
Use of
LATISSE®
more than once a day will not increase the growth
of eyelashes more than use once a day.
Store
LATISSE®
solution at
36
° to
77
°F (
2
° to
25
°C ).
General Information about LATISSE.®
Prescription treatments are sometimes prescribed for conditions
that are not mentioned in patient information leaflets. Do not use
LATISSE®
solution for a condition for which it was not prescribed.
Do not give
LATISSE®
to other people. It may not be appropriate
for them to use.
This leaflet summarizes the most important information about
LATISSE®
solution. If you would like more information, talk with your
physician. You can also call Allergan’s product information department
at
1
-
800
-
433
-
8871
.
W hat are the ingredients in LATISSE®?
Active ingredient:
bimatoprost
Inactive ingredients:
benzalkonium chloride; sodium chloride;
sodium phosphate, dibasic; citric acid; and purified water Sodium
hydroxide and/or hydrochloric acid may be added to adjust pH.The
pH during its shelf life ranges from 6.8 -
7
.
8
.
© 2010
Allergan. Inc.
. Irvine. C A
92612
. №
marks owned by Allergan.
Inc.
. U.S. Patents
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649
;
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351
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404
; and
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388.029
